Temperature mapping

Temperature mapping ensures confidence that refrigerators storing temperature-sensitive, often high-value medications consistently maintain the required conditions, even in real-world operating environments.

By characterizing temperature distribution inside a unit before it is shipped to a site, mapping identifies cold or warm spots, circulation issues, and the effect of loading — information that prevents costly product loss, protocol deviations, and risks to patient safety.

For sponsors and sites, a documented temperature map provides robust evidence for audits and inspections, demonstrating that storage conditions were validated and that cold-chain decisions were data-driven.

LABFISH’s temperature mapping service is carried out before shipment using nine certified, highly precise dataloggers placed at defined positions within the refrigerator to record temperatures continuously for 24 hours. Results are compiled into a clear, comprehensive protocol that shows location-specific temperature ranges and any excursions. For the most realistic assessment, we can pack the refrigerator with dummies to simulate operational loading and airflow, so the map reflects how the unit will behave in use — not just under empty-cabinet conditions.

The practical benefits are immediate: better protection for expensive biologics and investigational products, fewer surprises during site activation, and a stronger, traceable audit trail when combined with continuous temperature monitoring. Temperature mapping reduces the likelihood of spoilage, helps define where critical items should be placed inside the unit, and supports risk-based monitoring and contingency planning. 

For trials requiring the highest standards, we recommend pairing mapping with our on-site IQ/OQ service — together, they deliver installation verification, operational performance testing, and the comprehensive documentation package that inspectors expect.